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Continuous Expression of HIF-1α in Neural Stem/Progenitor Cells

Hypoxia-inducible factor-1 alpha subunit (HIF-1α) is a transcriptional activator mediating adaptive cellular response to hypoxia. Normally degraded in most cell types and tissues, HIF-1α becomes stable and transcriptionally active under conditions of hypoxia. In contrast, we found that HIF-1α is con...

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Detalhes bibliográficos
Main Authors: Roitbak, Tamara, Surviladze, Zurab, Cunningham, Lee Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629813/
https://ncbi.nlm.nih.gov/pubmed/20844947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-010-9561-5
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