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Neural stem/progenitor cells display a low requirement for oxidative metabolism independent of hypoxia inducible factor-1 alpha expression

Neural stem/progenitor cells (NSPCs) are multipotent cells within the embryonic and adult brain that give rise to both neuronal and glial cell lineages. Maintenance of NSPC multi-potency is promoted by low oxygen tension, although the metabolic underpinnings of this trait have not been described. In...

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Autori principali: Candelario, Kate M., Shuttleworth, C. William, Cunningham, Lee Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204647/
https://ncbi.nlm.nih.gov/pubmed/23410250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12204
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