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Alemtuzumab in multiple sclerosis: latest evidence and clinical prospects

Alemtuzumab was first used in multiple sclerosis in 1991. It is a monoclonal antibody which is directed against CD52, a protein of unknown function on lymphocytes. Alemtuzumab causes a lymphopenia, following which homeostatic reconstitution leads to prolonged alteration of the immune repertoire. Thi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kousin-Ezewu, Onajite, Coles, Alasdair
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629751/
https://ncbi.nlm.nih.gov/pubmed/23634277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040622313479137
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