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Alemtuzumab as Treatment for Multiple Sclerosis

Alemtuzumab, the first monoclonal antibody to be used as a therapy and the first to be humanized, was introduced into the treatment of multiple sclerosis in 1991 after its successful use in hematology, oncology, and transplantation medicine. One phase 2 and two phase 3 trials of this lymphocyte-depl...

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Pubblicato in:Cold Spring Harb Perspect Med
Autori principali: Katsavos, Serafeim, Coles, Alasdair
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169984/
https://ncbi.nlm.nih.gov/pubmed/29500306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a032029
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