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Increased rate of base substitution in a hamster mutator strain obtained during serial selection for gene amplification.
The pattern of mutations produced by a mutator gene (obtained during serial selection for amplification of the dihydrofolate reductase [dhfr] locus) shows a pronounced shift from that found in wild-type cells. The rate of certain types of base substitutions (particularly transitions) is dramatically...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1990
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362962/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2247084/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.12.6805 |
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