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Increased rate of base substitution in a hamster mutator strain obtained during serial selection for gene amplification.

The pattern of mutations produced by a mutator gene (obtained during serial selection for amplification of the dihydrofolate reductase [dhfr] locus) shows a pronounced shift from that found in wild-type cells. The rate of certain types of base substitutions (particularly transitions) is dramatically...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Caligo, M A, Armstrong, W, Rossiter, B J, Meuth, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2247084/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.12.6805
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