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Short Telomeres in ESCs Lead to Unstable Differentiation

Functional telomeres are critical for stem cell proliferation; however, whether they are equally important for the stability of stem cell differentiation is not known. We found that mouse embryonic stem cells (ESCs) with critically short telomeres (Tert(−/−) ESCs) initiated normal differentiation af...

詳細記述

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書誌詳細
主要な著者: Pucci, Fabio, Gardano, Laura, Harrington, Lea
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629568/
https://ncbi.nlm.nih.gov/pubmed/23561444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.01.018
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