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Aryl hydrocarbon induction of rat cytochrome P-450d results from increased precursor RNA processing.

We have previously demonstrated that cytochrome P-450d mRNA accumulation is induced at a posttranscriptional level by 3-methylcholanthrene (MCA) in primary cultures of rat hepatocytes grown in serum-free hormonally defined medium. Using dactinomycin chase experiments in this culture system, we found...

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Bibliografske podrobnosti
Main Authors: Silver, G, Krauter, K S
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC362955/
https://ncbi.nlm.nih.gov/pubmed/2247082
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