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Aryl hydrocarbon induction of rat cytochrome P-450d results from increased precursor RNA processing.

We have previously demonstrated that cytochrome P-450d mRNA accumulation is induced at a posttranscriptional level by 3-methylcholanthrene (MCA) in primary cultures of rat hepatocytes grown in serum-free hormonally defined medium. Using dactinomycin chase experiments in this culture system, we found...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Silver, G, Krauter, K S
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2247082/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.12.6765
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