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Recent advances in the molecular basis of frontotemporal dementia

Frontotemporal dementia (FTD) is a clinical syndrome with heterogeneous molecular basis. Until recently, our knowledge was limited to a minority of cases associated with abnormalities of the tau protein or gene (MAPT). However, in 2006, mutations in progranulin (GRN) were discovered as another impor...

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Detalhes bibliográficos
Main Authors: Rademakers, Rosa, Neumann, Manuela, Mackenzie, Ian R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629543/
https://ncbi.nlm.nih.gov/pubmed/22732773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2012.117
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