Attenuation of HIV-1 replication in macrophages by cannabinoid receptor 2 agonists

Infiltrating monocytes and macrophages play a crucial role in the progression of HIV-1 infection in the CNS. Previous studies showed that activation of the CB(2) can attenuate inflammatory responses and affect HIV-1 infectivity in T cells and microglia. Here, we report that CB(2) agonists can also a...

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Bibliographic Details
Main Authors: Ramirez, Servio H., Reichenbach, Nancy L., Fan, Shongshan, Rom, Slava, Merkel, Steven F., Wang, Xu, Ho, Wen-zhe, Persidsky, Yuri
Format: Artigo
Language:Inglês
Published: Society for Leukocyte Biology 2013
Subjects:
Host Defense & Pathophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629438/
https://ncbi.nlm.nih.gov/pubmed/23463725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1012523
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