Hyperphosphorylation of the retinoblastoma gene product is determined by domains outside the simian virus 40 large-T-antigen-binding regions.

With the murine retinoblastoma (RB) cDNA, a series of RB mutants were expressed in COS-1 cells and the pRB products were assessed for their ability (i) to bind to large T antigen (large T), (ii) to become modified by phosphorylation, and (iii) to localize in the nucleus. All point mutations and dele...

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Sonraí Bibleagrafaíochta
Main Authors: Hamel, P A, Cohen, B L, Sorce, L M, Gallie, B L, Phillips, R A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1990
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC362935/
https://ncbi.nlm.nih.gov/pubmed/2174110
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