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Suppression of epileptogenesis-associated changes in response to seizures in FGF22-deficient mice

In the developing hippocampus, fibroblast growth factor (FGF) 22 promotes the formation of excitatory presynaptic terminals. Remarkably, FGF22 knockout (KO) mice show resistance to generalized seizures in adults as assessed by chemical kindling, a model that is widely used to study epileptogenesis (...

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Main Authors: Lee, Clara H., Umemori, Hisashi
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629311/
https://ncbi.nlm.nih.gov/pubmed/23616746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00043
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