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Suppression of epileptogenesis-associated changes in response to seizures in FGF22-deficient mice

In the developing hippocampus, fibroblast growth factor (FGF) 22 promotes the formation of excitatory presynaptic terminals. Remarkably, FGF22 knockout (KO) mice show resistance to generalized seizures in adults as assessed by chemical kindling, a model that is widely used to study epileptogenesis (...

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Detalhes bibliográficos
Main Authors: Lee, Clara H., Umemori, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629311/
https://ncbi.nlm.nih.gov/pubmed/23616746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00043
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