The sirtuins, oxidative stress and aging: an emerging link

Reactive oxygen species (ROS) are a family of compounds that can oxidatively damage cellular macromolecules and may influence lifespan. Sirtuins are a conserved family of nicotinamide adenine dinucleotide (NAD+)-dependent protein deacetylases that regulate lifespan in many model organisms including...

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Bibliographische Detailangaben
Hauptverfasser: Merksamer, Philip I., Liu, Yufei, He, Wenjuan, Hirschey, Matthew D., Chen, Danica, Verdin, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2013
Schlagworte:
Research Perspective
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629286/
https://ncbi.nlm.nih.gov/pubmed/23474711
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