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Prospecting for Novel Plant-Derived Molecules of Rauvolfia serpentina as Inhibitors of Aldose Reductase, a Potent Drug Target for Diabetes and Its Complications

Aldose Reductase (AR) is implicated in the development of secondary complications of diabetes, providing an interesting target for therapeutic intervention. Extracts of Rauvolfia serpentina, a medicinal plant endemic to the Himalayan mountain range, have been known to be effective in alleviating dia...

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Detalhes bibliográficos
Main Authors: Pathania, Shivalika, Randhawa, Vinay, Bagler, Ganesh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629236/
https://ncbi.nlm.nih.gov/pubmed/23613832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061327
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