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Prospecting for Novel Plant-Derived Molecules of Rauvolfia serpentina as Inhibitors of Aldose Reductase, a Potent Drug Target for Diabetes and Its Complications

Aldose Reductase (AR) is implicated in the development of secondary complications of diabetes, providing an interesting target for therapeutic intervention. Extracts of Rauvolfia serpentina, a medicinal plant endemic to the Himalayan mountain range, have been known to be effective in alleviating dia...

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Библиографические подробности
Главные авторы: Pathania, Shivalika, Randhawa, Vinay, Bagler, Ganesh
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629236/
https://ncbi.nlm.nih.gov/pubmed/23613832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061327
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