Loss of CclA, required for histone 3 lysine 4 methylation, decreases growth but increases secondary metabolite production in Aspergillus fumigatus

Secondary metabolite (SM) production in filamentous fungi is mechanistically associated with chromatin remodeling of specific SM clusters. One locus recently shown to be involved in SM suppression in Aspergillus nidulans was CclA, a member of the histone 3 lysine 4 methylating COMPASS complex. Here...

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Autores principales: Palmer, Jonathan M., Bok, Jin Woo, Lee, Seul, Dagenais, Taylor R.T., Andes, David R., Kontoyiannis, Dimitrios P., Keller, Nancy P.
Formato: Artigo
Lenguaje:Inglês
Publicado: PeerJ Inc. 2013
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629006/
https://ncbi.nlm.nih.gov/pubmed/23638376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4
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