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Comparability of Mixed IC(50) Data – A Statistical Analysis
The biochemical half maximal inhibitory concentration (IC(50)) is the most commonly used metric for on-target activity in lead optimization. It is used to guide lead optimization, build large-scale chemogenomics analysis, off-target activity and toxicity models based on public data. However, the use...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628986/ https://ncbi.nlm.nih.gov/pubmed/23613770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061007 |
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