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Focal Scn1a knockdown induces cognitive impairment without seizures

Cognitive impairment is a common comorbidity in pediatric epilepsy that can severely affect quality of life. In many cases, antiepileptic treatments fail to improve cognition. Therefore, a fundamental question is whether underlying brain abnormalities may contribute to cognitive impairment through m...

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Détails bibliographiques
Auteurs principaux: Bender, Alex C., Natola, Heather, Holmes, Gregory L., Scott, Rod C., Lenck-Santini, Pierre-Pascal
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628954/
https://ncbi.nlm.nih.gov/pubmed/23318929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.12.021
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