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SCN1A mutations in Dravet syndrome: Impact of interneuron dysfunction on neural networks and cognitive outcome
Dravet syndrome (DS) is a childhood disorder associated with loss-of-function mutations in SCN1A and is characterized by frequent seizures and severe cognitive impairment. Animal studies have revealed new insights into the mechanisms by which mutations in this gene, encoding the type I voltage-gated...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307886/ https://ncbi.nlm.nih.gov/pubmed/22341965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yebeh.2011.11.022 |
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