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Early mitochondrial dysfunction leads to altered redox chemistry underlying pathogenesis of TPI deficiency
Triose phosphate isomerase (TPI) is responsible for the interconversion of dihydroxyacetone phosphate to glyceraldehyde-3-phosphate in glycolysis. Point mutations in this gene are associated with a glycolytic enzymopathy called TPI deficiency. This study utilizes a Drosophila melanogaster model of T...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2013
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628936/ https://ncbi.nlm.nih.gov/pubmed/23318931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.12.020 |
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