A 58-base-pair region of the human C3 gene confers synergistic inducibility by interleukin-1 and interleukin-6.

We have cloned the promoter for the human third component of complement (C3) gene and have identified sequences involved in its regulation during the acute-phase response. A construct linking 199 bp of the C3 promoter to the firefly luciferase gene was found to be very responsive to interleukin-1 (I...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Wilson, D R, Juan, T S, Wilde, M D, Fey, G H, Darlington, G J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362893/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2247055/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.12.6181-6191.1990
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