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microRNA-145 restores contractile vascular smooth muscle phenotype and coronary collateral growth in the metabolic syndrome

OBJECTIVE: Transient, repetitive occlusion stimulates collateral growth (CCG) in normal animals. Vascular smooth muscle cells (VSMCs) switch to synthetic phenotype early in CCG then return to contractile phenotype. CCG is impaired in the metabolic syndrome. We determined whether impaired CCG was due...

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書誌詳細
主要な著者: Hutcheson, Rebecca, Terry, Russell, Chaplin, Jennifer, Smith, Erika, Musiyekno, Alla, Russell, James C., Lincoln, Thomas, Rocic, Petra
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628919/
https://ncbi.nlm.nih.gov/pubmed/23393394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301116
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