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Evidence that Vpu Modulates HIV-1 Gag-Envelope Interaction towards Envelope Incorporation and Infectivity in a Cell Type Dependent Manner

The HIV-1 Vpu is required for efficient virus particle release from the plasma membrane and intracellular CD4 degradation in infected cells. In the present study, we found that the loss of virus infectivity as a result of envelope (Env) incorporation defect caused by a Gag matrix (MA) mutation (L30E...

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Hlavní autoři: Gautam, Archana, Bhattacharya, Jayanta
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628852/
https://ncbi.nlm.nih.gov/pubmed/23613843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061388
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