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Evidence that Vpu Modulates HIV-1 Gag-Envelope Interaction towards Envelope Incorporation and Infectivity in a Cell Type Dependent Manner

The HIV-1 Vpu is required for efficient virus particle release from the plasma membrane and intracellular CD4 degradation in infected cells. In the present study, we found that the loss of virus infectivity as a result of envelope (Env) incorporation defect caused by a Gag matrix (MA) mutation (L30E...

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書誌詳細
主要な著者: Gautam, Archana, Bhattacharya, Jayanta
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628852/
https://ncbi.nlm.nih.gov/pubmed/23613843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061388
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