Combined Approaches for Drug Design Points the Way to Novel Proline Racemase Inhibitor Candidates to Fight Chagas’ Disease

Chagas’ disease is caused by Trypanosoma cruzi, a protozoan transmitted to humans by blood-feeding insects, blood transfusion or congenitally. Previous research led us to discover a parasite proline racemase (TcPRAC) and to establish its validity as a target for the design of new chemotherapies agai...

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Bibliografiset tiedot
Päätekijät: Berneman, Armand, Montout, Lory, Goyard, Sophie, Chamond, Nathalie, Cosson, Alain, d’Archivio, Simon, Gouault, Nicolas, Uriac, Philippe, Blondel, Arnaud, Minoprio, Paola
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
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Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628851/
https://ncbi.nlm.nih.gov/pubmed/23613764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060955
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