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Carbolithiation of N-alkenyl ureas and N-alkenyl carbamates

N-Alkenyl ureas and N-alkenyl carbamates, like other N-acyl enamines, are typically nucleophilic at their β-carbon. However, by incorporating an α-aryl substituent, we show that they will also undergo attack at the β-carbon by organolithium nucleophiles, leading to the products of carbolithiation. T...

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Bibliografiske detaljer
Main Authors: Lefranc, Julien, Minassi, Alberto, Clayden, Jonathan
Format: Artigo
Sprog:Inglês
Udgivet: Beilstein-Institut 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628850/
https://ncbi.nlm.nih.gov/pubmed/23616806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.70
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