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Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put

Polycomb repressive complexes are conserved chromatin regulators with key roles in multicellular development, stem cell biology, and cancer. New findings advance molecular understanding of how they target to sites of action, interact with and alter local chromatin to silence genes, and maintain sile...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Simon, Jeffrey A., Kingston, Robert E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628831/
https://ncbi.nlm.nih.gov/pubmed/23473600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.02.013
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