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Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put

Polycomb repressive complexes are conserved chromatin regulators with key roles in multicellular development, stem cell biology, and cancer. New findings advance molecular understanding of how they target to sites of action, interact with and alter local chromatin to silence genes, and maintain sile...

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Bibliografiske detaljer
Main Authors: Simon, Jeffrey A., Kingston, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628831/
https://ncbi.nlm.nih.gov/pubmed/23473600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.02.013
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