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Isotridecanyl side chain of plusbacin-A(3) is essential for the transglycosylase inhibition of peptidoglycan biosynthesis()
Plusbacin-A(3) (pb-A(3)) is a cyclic lipodepsipeptide which exhibits antibacterial activity against multidrug-resistant Gram-positive pathogens. Plusbacin-A(3) is thought not to enter the cell cytoplasm and its lipophilic isotridecanyl side chain is presumed to insert into the membrane bilayer there...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628776/ https://ncbi.nlm.nih.gov/pubmed/23421534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4000222 |
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