Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls

Recent evidence suggests that inflammation plays a pivotal role in the development of lung cancer. In this study, we used a two-stage approach to investigate associations between genetic variants in inflammation pathways and lung cancer risk based on genome-wide association study (GWAS) data. A tota...

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Detalhes bibliográficos
Main Authors: Brenner, Darren R., Brennan, Paul, Boffetta, Paolo, Amos, Christopher I., Spitz, Margaret R., Chen, Chu, Goodman, Gary, Heinrich, Joachim, Bickeböller, Heike, Rosenberger, Albert, Risch, Angela, Muley, Thomas, McLaughlin, John R., Benhamou, Simone, Bouchardy, Christine, Lewinger, Juan Pablo, Witte, John S., Chen, Gary, Bull, Shelley, Hung, Rayjean J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628758/
https://ncbi.nlm.nih.gov/pubmed/23370545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-013-1270-y
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