Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls

Recent evidence suggests that inflammation plays a pivotal role in the development of lung cancer. In this study, we used a two-stage approach to investigate associations between genetic variants in inflammation pathways and lung cancer risk based on genome-wide association study (GWAS) data. A tota...

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Main Authors: Brenner, Darren R., Brennan, Paul, Boffetta, Paolo, Amos, Christopher I., Spitz, Margaret R., Chen, Chu, Goodman, Gary, Heinrich, Joachim, Bickeböller, Heike, Rosenberger, Albert, Risch, Angela, Muley, Thomas, McLaughlin, John R., Benhamou, Simone, Bouchardy, Christine, Lewinger, Juan Pablo, Witte, John S., Chen, Gary, Bull, Shelley, Hung, Rayjean J.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628758/
https://ncbi.nlm.nih.gov/pubmed/23370545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-013-1270-y
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