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Therapeutic potential of β-arrestin- and G protein-biased agonists

Members of the seven-transmembrane receptor (7TMR), or G protein-coupled receptor (GPCR), superfamily represent some of the most successful targets of modern drug therapy, with proven efficacy in the treatment of a broad range of human conditions and disease processes. It is now appreciated that β-a...

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Bibliografiska uppgifter
Huvudupphovsmän: Whalen, Erin J., Rajagopal, Sudarshan, Lefkowitz, Robert J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628754/
https://ncbi.nlm.nih.gov/pubmed/21183406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2010.11.004
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