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Depolarization of Mitochondria in Endothelial Cells Promotes Cerebral Vascular Vasodilation by Activation of Nitric Oxide Synthase

OBJECTIVE: Mitochondrial depolarization following ATP-sensitive potassium (mitoK(ATP)) channel activation has been shown to induce cerebral vasodilation by the generation of ‘calcium sparks’ in smooth muscle. It is unclear, however, if mitochondrial depolarization in endothelial cells is capable of...

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Detalhes bibliográficos
Main Authors: Katakam, Prasad V.G., Wappler, Edina, Katz, Paige, Rutkai, Ibolya, Institoris, Adam, Domoki, Ferenc, Gáspár, Tamás, Grovenburg, Samuel M., Snipes, James A., Busija, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628534/
https://ncbi.nlm.nih.gov/pubmed/23329133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300560
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