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Critical appraisal of the use of regorafenib in the management of colorectal cancer

The lack of valid clinical management options for patients affected by metastatic colorectal cancer, which has progressed after all approved standard treatments, has lead to research into new active molecules. Regorafenib is an oral small-molecule multi kinase inhibitor, binding to several intracell...

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Bibliografiska uppgifter
Huvudupphovsmän: Festino, Lucia, Fabozzi, Alessio, Manzo, Anna, Gambardella, Valentina, Martinelli, Erika, Troiani, Teresa, De Vita, Ferdinando, Orditura, Michele, Ciardiello, Fortunato, Morgillo, Floriana
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628528/
https://ncbi.nlm.nih.gov/pubmed/23610528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S34281
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