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Screening and identification of compounds with antiviral activity against hepatitis B virus using a safe compound library and novel real-time immune-absorbance PCR-based high throughput system

There are now 7 nucleoside/tide analogues, along with interferon-α, that are approved by the FDA for the management of chronic hepatitis B virus (HBV) infection, a disease affecting hundreds of millions of people worldwide. These medications, however, are limited in usefulness, and significant side...

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Autores principales: Lamontagne, Jason, Mills, Courtney, Mao, Richeng, Goddard, Cally, Cai, Dawei, Guo, Haitao, Cuconati, Andy, Block, Timothy, Lu, Xuanyong
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628437/
https://ncbi.nlm.nih.gov/pubmed/23415884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.02.001
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