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The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress

Secretory cargo that cannot fold properly in the ER are selectively targeted for removal by a well-studied ER-associated degradation pathway, or ERAD. In contrast, very little is known about post-ER quality control mechanisms for damaged or misfolded integral membrane proteins. Here we describe a qu...

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Autori principali: Zhao, Yingying, MacGurn, Jason A, Liu, Max, Emr, Scott
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628405/
https://ncbi.nlm.nih.gov/pubmed/23599894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00459
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