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Peptidergic CGRPα primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold

Calcitonin gene-related peptide (CGRP) is a classic molecular marker of peptidergic primary somatosensory neurons. Despite years of research, it is unknown if these neurons are required to sense pain or other sensory stimuli. Here, we found that genetic ablation of CGRPα-expressing sensory neurons r...

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Bibliografiske detaljer
Main Authors: McCoy, Eric S., Taylor-Blake, Bonnie, Street, Sarah E., Pribisko, Alaine L., Zheng, Jihong, Zylka, Mark J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628403/
https://ncbi.nlm.nih.gov/pubmed/23523592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.01.030
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