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Peptidergic CGRPα primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold

Calcitonin gene-related peptide (CGRP) is a classic molecular marker of peptidergic primary somatosensory neurons. Despite years of research, it is unknown if these neurons are required to sense pain or other sensory stimuli. Here, we found that genetic ablation of CGRPα-expressing sensory neurons r...

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Detalhes bibliográficos
Main Authors: McCoy, Eric S., Taylor-Blake, Bonnie, Street, Sarah E., Pribisko, Alaine L., Zheng, Jihong, Zylka, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628403/
https://ncbi.nlm.nih.gov/pubmed/23523592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.01.030
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