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Mutations changing tropomodulin affinity for tropomyosin alter neurite formation and extension

Assembly of the actin cytoskeleton is an important part of formation of neurites in developing neurons. Tropomodulin, a tropomyosin-dependent capping protein for the pointed end of the actin filament, is one of the key players in this process. Tropomodulin binds tropomyosin in two binding sites. Tmo...

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Detalles Bibliográficos
Main Authors: Moroz, Natalia, Guillaud, Laurent, Desai, Brinda, Kostyukova, Alla S.
Formato: Artigo
Idioma:Inglês
Publicado: PeerJ Inc. 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628370/
https://ncbi.nlm.nih.gov/pubmed/23638401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.7
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