Resveratrol Worsens Survival in SCID Mice With Prostate Cancer Xenografts in a Cell-Line Specific Manner, Through Paradoxical Effects on Oncogenic Pathways

BACKGROUND: Resveratrol increases lifespan and decreases the risk of many cancers. We hypothesized resveratrol will slow the growth of human prostate cancer xenografts. METHODS: SCID mice were fed Western diet (40% fat, 44% carbohydrate, 16% protein by kcal). One week later, human prostate cancer ce...

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Detalhes bibliográficos
Main Authors: Klink, Joseph C., Tewari, Alok K., Masko, Elizabeth M., Antonelli, Jodi, Febbo, Phillip G., Cohen, Pinchas, Dewhirst, Mark W., Pizzo, Salvatore V., Freedland, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628095/
https://ncbi.nlm.nih.gov/pubmed/23192356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22619
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