Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer

OBJECTIVES: To determine if a no-carbohydrate ketogenic diet (NCKD) and lactate transporter inhibition can exert a synergistic effect on delaying prostate tumour growth in a xenograft mouse model of human prostate cancer. MATERIALS AND METHODS: 120 nude athymic male mice (aged 6–8 weeks) were inject...

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Main Authors: Kim, Howard S., Masko, Elizabeth M., Poulton, Susan L., Kennedy, Kelly M., Pizzo, Salvatore V., Dewhirst, Mark W., Freedland, Stephen J.
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371292/
https://ncbi.nlm.nih.gov/pubmed/22394625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1464-410X.2012.10971.x
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