Combing signals from spontaneous reports and electronic health records for detection of adverse drug reactions

OBJECTIVE: Data-mining algorithms that can produce accurate signals of potentially novel adverse drug reactions (ADRs) are a central component of pharmacovigilance. We propose a signal-detection strategy that combines the adverse event reporting system (AERS) of the Food and Drug Administration and...

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Bibliografiske detaljer
Main Authors: Harpaz, Rave, Vilar, Santiago, DuMouchel, William, Salmasian, Hojjat, Haerian, Krystl, Shah, Nigam H, Chase, Herbert S, Friedman, Carol
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2013
Fag:
Research and Applications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628045/
https://ncbi.nlm.nih.gov/pubmed/23118093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2012-000930
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