Conditional Mutagenesis of Gata6 in SF1-Positive Cells Causes Gonadal-Like Differentiation in the Adrenal Cortex of Mice

Transcription factor GATA6 is expressed in the fetal and adult adrenal cortex and has been implicated in steroidogenesis. To characterize the role of transcription factor GATA6 in adrenocortical development and function, we generated mice in which Gata6 was conditionally deleted using Cre-LoxP recom...

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Hauptverfasser: Pihlajoki, Marjut, Gretzinger, Elisabeth, Cochran, Rebecca, Kyrönlahti, Antti, Schrade, Anja, Hiller, Theresa, Sullivan, Laura, Shoykhet, Michael, Schoeller, Erica L., Brooks, Michael D., Heikinheimo, Markku, Wilson, David B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2013
Schlagworte:
Glucocorticoids-CRH-ACTH-Adrenal
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628026/
https://ncbi.nlm.nih.gov/pubmed/23471215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1892
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