Cohesin-Dependent Association of Scc2/4 with the Centromere Initiates Pericentromeric Cohesion Establishment

Cohesin is a conserved ring-shaped multiprotein complex that participates in chromosome segregation, DNA repair, and transcriptional regulation [1, 2]. Cohesin loading onto chromosomes universally requires the Scc2/4 “loader” complex (also called NippedBL/Mau2), mutations in which cause the developm...

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Main Authors: Fernius, Josefin, Nerusheva, Olga O., Galander, Stefan, Alves, Flavia de Lima, Rappsilber, Juri, Marston, Adele L.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627958/
https://ncbi.nlm.nih.gov/pubmed/23499533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.02.022
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