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Tension-dependent removal of pericentromeric shugoshin is an indicator of sister chromosome biorientation

During mitosis and meiosis, sister chromatid cohesion resists the pulling forces of microtubules, enabling the generation of tension at kinetochores upon chromosome biorientation. How tension is read to signal the bioriented state remains unclear. Shugoshins form a pericentromeric platform that inte...

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Autors principals: Nerusheva, Olga O., Galander, Stefan, Fernius, Josefin, Kelly, David, Marston, Adele L.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066400/
https://ncbi.nlm.nih.gov/pubmed/24939933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.240291.114
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