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Tension-dependent removal of pericentromeric shugoshin is an indicator of sister chromosome biorientation

During mitosis and meiosis, sister chromatid cohesion resists the pulling forces of microtubules, enabling the generation of tension at kinetochores upon chromosome biorientation. How tension is read to signal the bioriented state remains unclear. Shugoshins form a pericentromeric platform that inte...

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Detalhes bibliográficos
Main Authors: Nerusheva, Olga O., Galander, Stefan, Fernius, Josefin, Kelly, David, Marston, Adele L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066400/
https://ncbi.nlm.nih.gov/pubmed/24939933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.240291.114
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