Inhibition of BCR/ABL Protein Expression by miR-203 Sensitizes for Imatinib Mesylate

Selective inhibition of BCR/ABL expression by RNA interference has been demonstrated as an effective strategy in CML treatment and a reversal to imatinib resistance. microRNAs (miRNAs) are small regulatory RNAs involved in post-transcriptional gene regulation. miR-203 is supposed to directly regulat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Yajuan, Yuan, Ying, Tao, Kun, Wang, Xin, Xiao, Qing, Huang, Zhenglan, Zhong, Liang, Cao, Weixi, Wen, Jianping, Feng, Wenli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627914/
https://ncbi.nlm.nih.gov/pubmed/23613955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061858
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