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Modeling the Neuroprotective Role of Enhanced Astrocyte Mitochondrial Metabolism during Stroke
A mathematical model that integrates the dynamics of cell membrane potential, ion homeostasis, cell volume, mitochondrial ATP production, mitochondrial and endoplasmic reticulum Ca(2+) handling, IP(3) production, and GTP-binding protein-coupled receptor signaling was developed. Simulations with this...
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Auteurs principaux: | , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
The Biophysical Society
2013
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627876/ https://ncbi.nlm.nih.gov/pubmed/23601322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.02.025 |
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