Light-induced Oxidation of Photoreceptor Outer Segment Phospholipids Generates Ligands for CD36-mediated Phagocytosis by Retinal Pigment Epithelium: A Potential Mechanism for Modulating Outer Segment Phagocytosis Under Oxidant Stress Conditions

Clearance by the retinal pigment epithelium (RPE) of shed photoreceptor outer segments (OSs), a tissue with one of the highest turnover rates in the body, is critical to the maintenance and normal function of the retina. We hypothesized that there is a potential role for photo-oxidation in OS uptake...

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Detalhes bibliográficos
Main Authors: Sun, Mingjiang, Finnemann, Silvia C., Febbraio, Maria, Shan, Lian, Annangudi, Suresh P., Podrez, Eugene A., Hoppe, George, Darrow, Ruth, Organisciak, Daniel T., Salomon, Robert G., Silverstein, Roy L., Hazen, Stanley L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627732/
https://ncbi.nlm.nih.gov/pubmed/16354659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M509769200
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