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Efficient identification of rare variants in large populations: deep re-sequencing the CRP locus in the CARDIA study
Effect sizes of many common single nucleotide polymorphisms identified in genome-wide association studies generally explain only a modest fraction of the total estimated heritability in a variety of traits. One hypothesis is that rare variants with larger effects might account for the missing herita...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627584/ https://ncbi.nlm.nih.gov/pubmed/23408856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt092 |
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